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July 2021



Problem and Solution:
Uniphage is a biotechnology company aiming to solve the problem of bacterial and fungal diseases worldwide. We start realizing this goal with the agricultural sector.

Our primary targets include some of the most dangerous and devastating bacterial plant diseases worldwide. Those diseases cause damage of $15 billion+ annually, and include citrus greening and various plant diseases in more than 400+ agriculturally important species caused by only 4 bacterial genus: Xylella, Xanthomonas, Phytoplasma, and Erwinia.

Uniphage uses AI to predict how to modify well-studied bacteriophages, viruses infecting only bacteria, against any bacterial pathogen. We use genomic data and known phage-bacteria interactions for our models. We will start lab testing early winter with an NUS grant.

Current progress:
Uniphage has received the NUS Innovation/Entrepreneurship Practicum Award, equity-free S$10.000; participated in the NSF-backed I-Corps Immersion Course and in the competitive programs by iGEM Entrepreneurship: Venture Creation Lab, Mentorship Program, and Fast-Track Program.

Uniphage is founded by two Yale-NUS seniors.

Sofia is a Life Sciences Major who has conducted biology research, from non-coding RNAs to biosensors. She was called a Biotech Leader Tomorrow, is an Amgen and Stanford AUI Scholar.

Chris Lis is a Yale-NUS Computer Science Major and full-stack web developer. For the past year, he has worked as a data scientist in a Silicon Valley Startup, Cuberg, and taken graduate-level Machine Learning classes at Stanford.

Uniphage has 3 advisors:
Yale-NUS Bioinformatics Professor Nathan Harmston
Yale-NUS Computational Biology Professor Maurice Cheung
Serial biotech entrepreneur Andres Cruz